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Stretch out. Meditation involves sitting in one spot for a certain period of time, so it is important to minimize any tension or tightness before you begin. Doing a couple of minutes of light stretching can really help to loosen you up and prepare both your body and mind for meditation. It will also prevent you from focusing on any sore spots instead of relaxing your mind.
Remember to stretch your neck and shoulders, especially if you've been sitting in front of a computer, and don't forget your lower back. Stretching out your legs, particularly those on the inner thigh, can be helpful when meditating in the lotus position.
More information on specific stretching techniques can be found here.